Afatinib

Overview

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Identification

CN(C)C/C=C/C(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)O[C@H]4CCOC4

InChI=1S/C24H25ClFN5O3/c1-31(2)8-3-4-23(32)30-21-11-17-20(12-22(21)34-16-7-9-33-13-16)27-14-28-24(17)29-15-5-6-19(26)18(25)10-15/h3-6,10-12,14,16H,7-9,13H2,1-2H3,(H,30,32)(H,27,28,29)/b4-3+/t16-/m0/s1

Safety & Regulations

• WarningH302 (50%): Harmful if swallowed [Warning Acute toxicity, oral]
• WarningH315 (50%): Causes skin irritation [Warning Skin corrosion/irritation]
• WarningH319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
• WarningH335 (50%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
• WarningH373 (50%): May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]

Storage Conditions

Store at ambient temperature and humidity (2–8 °C).