Overview

IDCS-8e20f74ea37d
CAS RN95058-81-4
Synonyms gemcitabine
95058-81-4
2'-Deoxy-2',2'-difluorocytidine
2',2'-Difluorodeoxycytidine
dFdC
Gemcitabina
Gemcitabinum
LY-188011
LY188011
2',2'-difluoro-2'-deoxycytidine More…

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Identification

Molecular FormulaC9H11F2N3O4
Molecular Weight263.20 g/mol
CAS Number95058-81-4
IUPAC Name

4-amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one

C1=CN(C(=O)N=C1N)[C@H]2C([C@@H]([C@H](O2)CO)O)(F)F
InChI=1S/C9H11F2N3O4/c10-9(11)6(16)4(3-15)18-7(9)14-2-1-5(12)13-8(14)17/h1-2,4,6-7,15-16H,3H2,(H2,12,13,17)/t4-,6-,7-/m1/s1

SDUQYLNIPVEERB-QPPQHZFASA-N

Safety & Regulations

⚠ Warning Handle according to recommended safety guidelines.
  • WarningH302 (20%): Harmful if swallowed [Warning Acute toxicity, oral]
  • WarningH312 (40%): Harmful in contact with skin [Warning Acute toxicity, dermal]
  • WarningH315 (80%): Causes skin irritation [Warning Skin corrosion/irritation]
  • WarningH319 (80%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
  • WarningH335 (20%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
  • DangerH340 (40%): May cause genetic defects [Danger Germ cell mutagenicity]
  • WarningH351 (20%): Suspected of causing cancer [Warning Carcinogenicity]
  • DangerH360 (20%): May damage fertility or the unborn child [Danger Reproductive toxicity]
  • DangerH360FD (20%): May damage fertility; May damage the unborn child [Danger Reproductive toxicity]
  • WarningH361 (40%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]
  • WarningH361fd (20%): Suspected of damaging fertility; Suspected of damaging the unborn child [Warning Reproductive toxicity]
  • DangerH372 (20%): Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]
  • WarningH373 (20%): May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]
  • H411 (20%): Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]

Storage Conditions

Store at ambient temperature and humidity (2–8 °C).

View Literature on PubChem
Gemcitabine

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